Vitamin C Beneficial In Heart Disease A DGReview of :"Vitamin C Preserves Endothelial Function in Patients with Coronary Heart Disease after a High-Fat Meal" Clinical Cardiology 05/27/2002 By Robert Short Vitamin C treatment has a possible role in benefiting patients with coronary heart disease by countering the adverse effects of a high-fat meal. The postprandial serum triglyceride concentration is raised after a high-fat meal and this postprandial state is critical in atherogenesis, inducing endothelial dysfunction through an oxidative stress mechanism. These were the findings of a study that included 74 patients with coronary heart disease and 50 people without the disease but who had risk factors. These two groups were split into subgroups: those who received 2 g of vitamin C and those who did not after eating high-fat meal. The study was conducted by Dr Ling Liu, Department of Cardiology, Hunan University, Hunan, People's Republic of China, and co-workers. They found that postprandial serum triglyceride concentration increased significantly at two to five hours after the high-fat meal in all groups. The fasting flow-mediated dilatation and nitroglycerin-induced dilatation of patients with coronary heart disease were impaired compared with those without disease. Although the postprandial flow-mediated dilatation was significantly aggravated in people not taking vitamin C (both with and without heart disease), this parameter in patients and subjects taking vitamin C showed no significant change. Clin Cardiol 2002;25:219-224. "Vitamin C Preserves Endothelial Function in Patients with Coronary Heart Disease after a High-Fat Meal" Thanks to docguide.com Psychopharmacology, 9/02 Ann Sug, 12/02 Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.