Update-9/01

CAMBRIDGE, Mass. -- A breast-cancer treatment based on MIT radar research is now in Phase II clinical trials, and preliminary results to be reported at a September 24 meeting look promising.

In the treatment, microwave radiation is focused externally on the breast, heating and killing tumor cells within. "After thermotherapy treatment, we are seeing significant breast cancer cell kill without damage to the skin," said Dr. Robert A. Gardner, MD, of the initial Phase II results. Gardner is a breast surgeon at Columbia Hospital’s Center for Breast Care in West Palm Beach, Florida, one of three hospitals currently participating in the trials.

At the 24th International Congress on Clinical Hyperthermia in Rome, Italy, September 24-29, Gardner and other clinical researchers involved in the study will present the results for thermotherapy of four women with early-stage breast cancer. The Phase II trial should be completed in 2002 with the treatment of 39 other women at Columbia Hospital, Martin Luther University in Halle, Germany, and Harbor-UCLA Medical Center in California.

A second Phase II trial for 90 patients with locally advanced breast cancer should begin this month at Columbia Hospital. Martin Luther University is also accepting patients. This trial, too, is expected to be completed in 2002.

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