Successful treatment of intractable hiccup with methylphenidate in a lung cancer patient R. Maréchal1, T. Berghmans1, 2, and J. P. Sculier1 (1) Department of Internal Medicine, Institut Jules Bordet, Centre des tumeurs de l'Université Libre de Bruxelles, Brussels, Belgium (2) Contact address: Department of Internal Medicine, Institut Jules Bordet, Rue Héger Bordet, 1, 1000 Bruxelles, Belgium Abstract. In a 56-year-old man with metastatic small-cell lung cancer, a persistent hiccup was refractory to classic treatments. Hyponatremia, neoplasic mediastinal involvement and liver metastases were though to be potential causative factors. Methylphenidate (MTP), a mild central nervous system (CNS) stimulant that is most commonly used for the treatment of attention deficit hyperactivity disorder, was started at a daily dose of 10 mg. It was rapidly efficient and well tolerated. This report suggests a potential advantage of MTP in the treatment of intractable hiccup in cancer patients. J Supportive Care Cancer, 2/03 From an email Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.