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Science: Smoking of cannabis does not increase risk for oral
cancer
Contrary to previous research findings cannabis smoking does
not appear to be associated with an increased risk of developing
oral cancer, according to a large study from the USA.
The
results appeared in the June issue of Cancer Research. The
study of Dr. Karin A. Rosenblatt and colleagues found no
association between cannabis use and increased oral-cancer
risk, regardless of how long, how much or how often a person
has used cannabis.
"When asking whether any marijuana use puts you at increased
risk of oral cancer, our study is pretty solid in saying there's
nothing going on there," said Dr. Stephen M. Schwartz, one of
the authors of the study.
But because the incidence of extensive,
long-term cannabis use was low among the study population it is
unclear whether extremely heavy use over many years is related
to the risk for oral cancer, Schwartz said.
The study involved
407 oral-cancer cases and 615 healthy control subjects from the
state of Washington who had been interviewed in detail about
their history of marijuana use, among other lifestyle factors.
Participants ranged in age from 18 to 65.
The new study counters findings from a smaller investigation with
173 oral cancer patients, published in 1999, which suggested
that ever-users of marijuana were at more than twice the risk of
getting head-and-neck cancer as compared to non-users.
The
earlier study had a number of limitations, most importantly the
fact that its control, or comparison, group was comprised of
individuals who had donated blood at the same hospital where
the oral-cancer cases had been treated.
Blood donors tend to
have fewer high-risk habits than the general population.
(Sources: Rosenblatt KA, et al.
Marijuana use and risk of oral
squamous cell carcinoma.
Cancer Res 2004;64:4049-54.
Press
release of the Fred Hutchinson Cancer Research Center of 1
June 2004)
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