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RACIAL DISPARITY IN PROSTATE-CANCER
DIAGNOSES NARROWING AFTER PSA
The PSA era may be auguring well for African-
American men.
In a study of 195 African-American men and 587 Caucasians who had
a radical prostatectomy for clinically localized prostate carcinoma
in a major Army hospital, the traditional racial gap eroded steadily
from 1988 to 1999 in the rates of extracapsular extension, positive
margins, pretreatment PSA levels, and age at the time of surgery.
The percentage of African-American men with extracapsular extension
decreased from 100% in 1988-89 to 34.8% in 1998-99 and for white men
from 56.9% to 43.2%, Dr. Judd W. Moul of Walter Reed Army Medical
Center's Center for Prostate Disease Research here and colleagues
reported in the Nov. 15 Cancer.
The rate of positive margins for African-American men declined from
100% for the 1988-89 year group to 26.1% for the 1998-99 year group,
they reported, and the rate of positive margins for white men fell
from 41.2% to 27.0%.
The mean age at surgery decreased from 66.6 to 59.9 for African-
American men and from 65.9 to 61.1 for white men, they found. For PSA
levels at diagnosis, the decrease was from 16.5 to 6.5 ng/dL for
African-American men and from 10.1 to 6.6 ng/dL for white men.
The investigators concluded that the decreases in extracapsular
extensions and positive margins in African-American men are "primarily
because of PSA testing, coupled with improved public awareness and
equal access to care."
They said that if an African-American man
asks a clinician to make the decision on whether PSA testing should
be done, it should be done.
(Sorry we neglected to record where we found this article.)
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