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Prozac (Fluoxetine) Effective for Hot Flashes Post-Breast Cancer
Treatment
ROCHESTER, MN -- March 15, 2002 -- A Mayo Clinic study indicates
that Prozac (fluoxetine) can safely and significantly relieve
hot flashes in women who have been treated for breast cancer.
In this eight-week study, women experienced a 50 percent decrease
in the frequency and severity of hot flashes while taking Prozac
for the first four weeks of the study. Women randomized to receive
a placebo during the first four weeks noted a 36 percent decrease
in their hot flashes. Both groups of women were switched to the
alternative substance (placebo or Prozac) during the second four-week
study period.
The findings of this study are published in the
March 15 issue of the Journal of Clinical Oncology.
"Our findings
provide proof of principle that some of the newer antidepressants
can relieve hot flashes," says Charles Loprinzi, MD, a Mayo Clinic
medical oncologist and lead researcher on the study.
[03/18/2002; Doctor's Guide]
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