Dr. William Grant of the Sunlight, Nutrition and Health Research Center (SUNARC), San Francisco, suggests maintaining a high dietary antioxidant status in order to guard against skin cancer. (posted 6/05) Protective Effects of Topical Antioxidants in Humans Dreher F, Maibach H Curr Probl Dermatol. 2001;29:157-164 Human studies have convincingly demonstrated pronounced photoprotective effects of 'natural' and synthetic antioxidants when applied topically before UVR exposure. Particularly with respect to UVB-induced skin damage such as erythema formation, the photoprotective effects of antioxidants are significant when applied in distinct mixtures in appropriate vehicles. Topical application of such combinations may result in a sustained antioxidant capacity of the skin, possibly due to antioxidant synergisms. And, since UVA-induced skin alterations are believed to be largely determined by oxidative processes, topical administration of antioxidants might be particularly promising. In fact, topical application of antioxidants or antioxidant mixtures resulted in a remarkable increase in the minimal dose to induce immediate pigment darkening after UVA exposure and diminished the severity of UVA-induced photodermatoses in humans. In conclusion, regular application of skin care products containing antioxidants may be of the utmost benefit in efficiently preparing our skin against exogenous oxidative stressors occurring during daily life. Furthermore, sunscreening agents may also benefit from combination with antioxidants resulting in increased safety and efficacy of such photoprotective products. Int J Oncol, 8/01 Green Tea EGCG on Mouse Skin Protective Articles, studies, LINKS Patterns of Recurrence After SNLB:Cutaneous Melanoma Curcumin & Irreversible Growth Inhibition/Apoptosis:Melanoma Diet & Risk of Malignant Melanoma Symptoms Pts w/cncrrnt BioChemothrpy Malign Melanoma Toenail Arsenic Content & Cutaneous Melanoma: Iowa Lymphedema After Complete Node Dissection: Melanoma Gray Hair Shares Genetic Root w/Melanoma Canavaxin (TM) for Stage IV Melanoma CANCELLED Risk of Melanoma & Vitamin A, Coffee, Alcohol Wasabi product Shows Action in Melanoma Cells Antiangiogenic: Andrographis paniculata extract & andrographolide Melanoma Can Appear in 'Hidden' Places Too Do Sunscreens Increase Risk of Melanoma in Populations Residing at Higher Latitudes? Dispelling myth of “benign hair sign” for melanoma Genetic Manifestation of Melanoma Linked to Geographic Location Phtoochem Photobiol, 2001 Curr Probl Dermatol, 2001 Chemoprevention w/Alpha-tocopherol & Mice Burns, 2001 Compound from Corn Lily For Skin Cancer Skin Pharmacol Appl Skin Physiol, 2001 Toxicol Lett, 2001 Dermatol Surg, 2001 Topical Vitamin C Stops Basal Cell Carcinoma Healthscout, 10/01 LINK for cream to TREAT Non-Melanoma Skin Cancers Research shown British J Cancer, 12/04 2001 Summary Basal Cell Ca Does Not Correlate with Most-Exposed Areas Nature News Service, Dec 2001 JNCI, 2/02 Tanning Associated with Optimal Vit D Status J Clinical Oncology, 1/02 Soc for Investigative Dermatology, 5/02 National Acad of Sciences, 8/02 Univ of Central Florida, 6/03 Book from Indian publishers AACR Press Release, 10/03 Frontiers in Cancer Prevention Research, 2003 EGCG, Chemoprevention & Skin Ca Chemopreventive Effects Betanin: Skin Ca (Mice) Calcium Glucorate & Skin Tumors Ultraviolet Rad B & Perillyl Alcohol Thanks to www.ivanhoe.com J Am Acad of Dermatology, 11.06 Skin Ca: Lack of Awareness in Minority Communities Dermatology Technique not Good for Dark Skin Locate their links here Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.