Ed leads a group interested in alternative therapies. I asked him if the PSA reading is important. "Regarding PSA and its meaning, all I can say is that for the vast majority on PC SPES the reading is meaningful. We usually try to get a really low number for close to a year and then slowly start reducing the dose (1) capsule per month while following our PSA to be sure it stays low. There seems to no hard and fast rule for all cases but this works for most, I've been around 0.5 for well over a year now and have reduced to just (2) per day but every one is different." Remember Ann is NOT A Doctor and has NO medical training.