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Risk of BrCa  and Melatonin Issues

Risk of breast cancer among Norwegian women with visual impairment

J. Kliukiene, T. Tynes, A. Andersen

Abstract

Experimental studies suggest that melatonin has a protective effect against breast cancer. Exposure to light suppresses melatonin secretion, but to a lesser degree in totally blind persons.

Breast cancer was investigated in a cohort of 15 412 Norwegian visually impaired women. The risk among totally blind women was 0.64 (95% CI = 0.21-1.49, 5 cases only), and for those who became blind before age of 65, the SIR was 0.51 (95% CI = 0.11-1.49).

Our findings give support to the 'melatonin hypothesis'.

British Journal of Cancer p 397-399, Volume 84, Number 3, February 2001


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padUrinary Melatonin Levles & BCa Risk
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JNCI, 7/05
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