Reported by Marilyn Holasek Lloyd (AMAZON listserv) Comprehensive Cancer Care June, 2000 Notes taken from talk given by Dr. Nickolas Gonzalez Dr. John Beard was a physician at the University of Edinburg around the turn of the century. He was fascinated with the study of placentas. He studied Nutritive Trophic factors, gluteal hormones, progesterone, FSH and estrogen. After fertilization, Enzymes and the blastocyst produces enzymes protease and protelytic enzymes which allow egg to implant. Trophoblastic cells physically invade uterus. 1. Microscopically they appear like cancer cells--trophoblastic. This is what interested Beard so much 2. They behave like cancer cells--lose differentiation. Cancer cells do that the more malignant they become. Dr. G said aggressive cancer like breast cancer --you can't tell where it comes from--it is so undifferentiated. 3. By 1900-Beard was absolutely fascinated and intrigued with all of this. Dr. G went on to say the lining of the large intestine is replaced every 5 days. The cells grow and stop growing like they should (Ulcerative colitis is out of control stuff) Cancer cells don't stop growing like they should. 4 linings of large intestine submucosa mucilaginous, crypts of librica-(-which is a reservoir of stem cells which are undifferentiated cells--every tissue and glad has stem cells.) the actual lining and crypts. The stem cells migrate up the crypts--differentiate and become the lining of the intestine. Behavior of stem cells as they move up crypt is they lose their immortality. When migration goes awry, they don't differentiate--continue to become primitive adenomas and this leads to tumors. They become invasive--they have produced a blood supply. Cancer produces its own sets of enzymes--then it gets is blood supply--angiogenesis and then it becomes immunologically protected with type 1 or type 2 antigens. So cancer Invades, grows, has blood supply and is immunologically protected. Trophoblasts growth is intense--back to human growth from conception. It has to produce its own blood supply which is the point of the placenta an angeogenesis dream. It is not rejected by mother and the tissue invades the mother's uterus. Now there is such a thing as hydatiform mole and chroicarcinoma where the Trophoblasts grow uncontrollably in uterus. Death comes to mother in 8-12 weeks. Gradually at some point this Trophoblasts becomes differentiated--What was the controlling element? This is where Beard's genius comes in. He made the observation that it comes from the fetal pancreas. The pancreas is in the retro peritoneal space. It has a head and a tail. The endocrine part produces hormones insulin (alpha and beta) glycogen, breaks down surgar, somatostatin suppresses insulin The exocrine part of the pancreas produces enzymes--through ducts and tubules. Enzymes for digestion and proteolytic enzymes. Trypsin, Cryatrypsin??? protease amylase etc. These enzymes are powerful--to the point that they could digest the pancreas. Tryypsinogen is what protects the pancreas from itself. The signals are two fold. The vagus nerve--wanderer nerve of the parasympathetic system is turned on affecting every cell in pancreas and releasing pancreatic enzymes into the ducts. The hormones secretin influence circulation in the blood. Cholesystokinase only works in alkaline environment. Neutralizes acid. Now here is the important part. The fetal pancreas starts working and secreting enzymes at the 56th day of gestation. Fetus' don't digest anything till they are born. Beard wondered why did God start this pancreas in the fetus working so early? HE FOUND THE DAY THE PANCREAS STARTED WORKING IN THE FETUS IS THE DAY THE PLACENTA STOPS GROWING In 1902 Beard wrote about the Trophoblastic theory of cancer and he was BLASTED by medicine. By 1906 he started writing about and saying PANCREATIC ENZYMES SHOULD BE USED TO TREAT CANCER--medicine balked and said he was crazy He said that cancer cells come from stem cells that are uncontrolled stem cells. They are undifferentiated and need to differentiate. He said that trophoblastic cells from our conception and growth remain in our body. That they are misplaced in our body throughout life. 3 billion of these germ cells don't make it. These germ and trophoblastic cells which are misplaced placental cells exist in our own bodies. (BY the way he was really blasted saying this and now a hundred years later the technology of looking at small particles has confirmed this) BEARD SAID, IF YOU DON'T HAVE ENOUGH PANCREATIC ENZYMES, THESE TROPHOBLASTIC CELLS WILL GROW. Beard discovered stem cells when medicine was primitive. Dr. G said this was an outstanding discovery Now there was a cancer model which Medicine used to test cancer substances--it was called the Jenson Mouse model. Sarcoma transplanted onto a mouse. Sarcoma's are deadly (cancer of connective tissue etc.) Beard got the most prestigious drug company in England to manufacture pancreatic enzymes for him. He hunted at the stock yards to find the right animals He tested these pancreatic enzymes on the mice and stopped their cancer. 1911 He also noted that nothing is more toxic to the body as dead cancer cells. (This set up the thinking later that was to include detoxifying the body in cancer treatment) He wrote about the enzymatic treatment of cancer--was black balled in medicine and died in obscurity in 1924. The doctors at the time said that the mice didn't have sarcoma whereas this model was used in all research in Europe. Beard's work was resurrected by a Doctor from Columbia Frances Pottinger. This will be part two and shows how nervous system study tied in with the pancreatic enzyme study of cancer which led to Kelly's original treatment--It was the orthodontist Kelly who cured himself of pancreatic cancer, and whose work Gonzalez originally studied. Respectfully submitted Part II-Gonzalez Method More from Marilyn H. Lloyd Audience reactions per Marilyn 2000 Conference notes Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.