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ABSTRACT: Mammographic Parenchymal Patterns and Self-reported
Soy Intake in Singapore Chinese Women
The study aimed to investigate whether self-reported dietaryvariables
were associated with mammographic parenchymal patterns, which
have been shown to predict risk of breast cancer.
Among the 3,421
women, ages 45-74 years, common to two independent population-based
cohorts, mammographic parenchymal patterns and current dietary
habits were assessed for 406 randomly chosen participants.
Logistic
regression methods were used to compare dietary and other lifestyle
profiles between subjects classified as displaying high (cases)
and low risk (controls) parenchymal patterns.
After adjustment
for energy intake and other potential confounders, dietary soy
protein intake was inversely related to risk of high-risk parenchymal
pattern (odds ratio, 0.41; 95% confidence interval, 0.18-0.94,
highest versus lowest quartile of intake).
Similarly, the highest
versus lowest quartile of dietary soy isoflavone intake was significantly
related to low-risk parenchymal patterns (odds ratio, 0.44; 95%
confidence interval, 0.20-0.98).
The association between
high soy intake and a reduced risk of mammographic parenchymal
patterns that are associated with high breast cancer risk may
have important implications in breast cancer prevention.
[07/08/2002; Cancer Epidemiology, Biomarkers and Prevention]
Ann's NOTE: Eating soy seems to show that there is less density in the breast tissue. This makes it easier to read a mammogram and may have other implications.
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