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Lecture on Pathology Issues - Dr. Shahla Masood

Dr. Masood is the founder of the International Society for Breast Pathology.

Ann Fonfa heard the lecture by Shala Masood, MD (Department of Pathology and Laboratory Medicine, University of Florida, College of Medicine, Jacksonville, FL)at the 2006 San Antonio Breast Cancer Symposium.

Here are some excerpts from her talk:

26% of HER2 status is misjudged

Only 58% of 6 pathologists agree on a diagnosis, 71% if 5 of 6, and 92% for 4 of 6.

There is very low reimbursement for Pathologists.

Is Ductal Hyperplasia actually different from low level DCIS?

A five-year follow up of Atypical Hyperplasia showed no development of cancer in various studies, including one that went ten years out.

A very small number of pathologists actually follow the guidelines.

She strongly suggests a second opinion with a cancer diagnosis. The information may impact outcome, change in planned sugery or prognostic information.

Dr. Masood stated that biomarkers are needed for pathology. Pathologists need to be better integrated into the totality of breast cancer treatment.


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padReview of the pathological features of 164 cases LCIS
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Abstract #4013 SABCS 12/06
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pad Increasing Diagnosis of breast cancer Risk Markers: Atypia & LCIS
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Abstract #5044 SABCS 12/06
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