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ABSTRACT: Histological Subtypes of Ductal Carcinoma in situ of
the Breast
Background: It has become common to divide ductal carcinoma in
situ (DCIS) of the breast into two main groups, comedo or noncomedo
by tumor morphology. But noncomedo DCIS can be further stratified
into several morphological patterns that exhibit several different
growth patterns and most DCIS lesions have more than one pattern.
In this study, DCIS elements were classified by morphological
pattern and the association between predominant or recessive
elements of DCIS lesions and clinicopathological findings was
evaluated.
Conclusions: DCIS lesions containing a comedo or cribriform element
are more likely to have microscopic spread and involvement of
lobules and DCIS lesions containing a papillary element are likely
to be multicentric, whether the pattern are predominant in the
tumor or not.
[03/01/2002; The Journal of the Japanese Breast Cancer Society]
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