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Editorial on this Study-JAMA

EDITORIAL: Does an Apple a Day Keep Breast Cancer Away? [02/14/2001; Journal of the AMA

Can an apple a day keep breast cancer away? The latest answer to this question, based on an analysis of data reported by Smith-Warner and colleagues in this issue of THE JOURNAL, is "no."

However, anyone closely monitoring this question can find conflicting conclusions in the literature. Examining data from numerous epidemiological studies, the World Cancer Research Fund concluded that the evidence that fruits and vegetables may reduce the risk of oral, pharyngeal, esophageal, lung, stomach, and colon cancer was convincing and that the evidence for an association between intake of fruits and vegetables with breast, pancreatic, and bladder cancer was probable.

Since release of the World Cancer Research Fund report, several studies, including the one by Smith-Warner and colleagues, have challenged the findings that were the basis for the 1997 report. In contrast to a meta-analytic approach in which risk estimates are derived from published data, the data used by Smith-Warner and colleagues in the Pooling Project of Prospective Studies of Diet and Cancer were obtained directly from participating cohort studies.

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