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EDITORIAL: Does an Apple a Day Keep Breast Cancer Away?
[02/14/2001; Journal of the AMA
Can an apple a day keep breast cancer away? The latest answer
to this question, based on an analysis of data reported by Smith-Warner
and colleagues in this issue of THE JOURNAL, is "no."
However,
anyone closely monitoring this question can find conflicting
conclusions in the literature. Examining data from numerous epidemiological
studies, the World Cancer Research Fund concluded that the evidence
that fruits and vegetables may reduce the risk of oral, pharyngeal,
esophageal, lung, stomach, and colon cancer was convincing and
that the evidence for an association between intake of fruits
and vegetables with breast, pancreatic, and bladder cancer was
probable.
Since release of the World Cancer Research Fund report,
several studies, including the one by Smith-Warner and colleagues,
have challenged the findings that were the basis for the 1997
report. In contrast to a meta-analytic approach in which risk
estimates are derived from published data, the data used by Smith-Warner
and colleagues in the Pooling Project of Prospective Studies
of Diet and Cancer were obtained directly from participating
cohort studies.
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