Major Dietary Patterns and the Risk of Colorectal Cancer in Women Teresa Fung, ScD; Frank B. Hu, PhD, MD; Charles Fuchs, MD; Edward Giovannucci, ScD, MD; David J. Hunter, ScD, MBBS; Meir J. Stampfer, DrPH, MD; Graham A. Colditz, DrPH, MD; Walter C. Willett, DrPH, MD Background Several foods and nutrients have been implicated in the development of colon and rectal cancers. In this study, we prospectively assessed the associations between major dietary patterns and the risks of these 2 cancers in women. Methods Using dietary information collected in 1984, 1986, 1990, and 1994 from 76 402 women aged 38 to 63 years without a history of cancer in 1984, we conducted factor analysis and identified 2 major dietary patterns: "prudent" and "Western." We calculated factor scores for each participant and examined prospectively the associations between dietary patterns and colon and rectal cancer risks. Results The prudent pattern was characterized by higher intakes of fruits, vegetables, legumes, fish, poultry, and whole grains, while the Western pattern, by higher intakes of red and processed meats, sweets and desserts, french fries, and refined grains. During 12 years of follow-up, we identified 445 cases of colon cancer and 101 cases of rectal cancer. After adjusting for potential confounders, we observed a relative risk for colon cancer of 1.46 (95% confidence interval, 0.97-2.19) when comparing the highest with the lowest quintiles of the Western pattern (P value for trend across quintiles, .02). The prudent pattern had a nonsignificant inverse association with colon cancer (relative risk for fifth quintile compared with the first, 0.71; 95% confidence interval, 0.50-1.00; P for trend across quintiles, .31). We did not observe any significant association between dietary patterns and rectal cancer. Conclusion We found a significant positive association between the Western dietary pattern and the risk of colon cancer. Arch Intern Med. 2003;163:309-314 Ann's NOTE: With most studies of this type, they rarely have participants who eat a lot of fruits/vegetables (by a lot read minimum National Cancer Institute "5 A Day" recommendation. We can only imagine the value of such a diet rich in phytochemicals, antioxidants and all the other benefits to be found in fruits and vegetables. Abstract 3983 and Abstract 3986 FISHGASTRO Study Am J Clin Nutr, 2/04 Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.