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Depth of Tumor Invasion a Factor

The April issue of Cancer had a study on the depth of tumor invasion as a predictor of recurrent disease in the esophagus.

The study looked at 439 people who had complete resection of their esophagus in a French Hospital. These people were patients from January, 1982 through July, 2002.

Average follow-up was a little more than three years. A little over half of the patients developed recurrence.

The median time to recurrence was 12 months and the median survival after recurrence was seven months. Overall survival in this group was 91% at one year and 41% at 5 years. On multivariate analysis, the only factor that was found to predict recurrent disease was the depth of tumor invasion based on histologic assessment (p = 0.001), the investigators note.

Study authors were Dr. Jean-Pierre Triboulet and colleagues, from Hopital Claude Huriez in Lille, France.



Cancer 2003;97:1616-1623.

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