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RSNA: Cryosurgery Turns Bone Metastases Into Iceballs Of Dead
Tissue
CHICAGO, IL -- November 30, 2001
Researchers report
success in destroying bone and soft tissue metastases
with cryosurgery guided with magnetic resonance imaging.
In his oral presentation, lead author Sridhar Sankar, MD, a clinical
fellow in magnetic resonance imaging at Brigham and Women's Hospital,
Boston, Massachusetts, reported on treatment of eight patients
with cryotherapy.
Under MRI guidance, doctors placed a tiny hollow
needle into the tumor. Through that needle they pumped pressurized
argon gas that reached a temperature of minus-150 degree Celsius,
Dr. Sankar said. "The cold gathers moisture from surrounding
tissue forming an iceball that encompasses the entire tumor-killing
it," he explained "There are many methods of killing tumors with
heat, radiofrequency or cryosurgery," said Stuart Silverman,
MD, associate professor of radiology at Harvard Medical School,
"and all these methods appear effective. But I prefer this cryosurgery
techniques because we can actually see what we are doing as the
procedure is performed."
Dr. Silverman said that by taking magnetic
resonance imaging (MRI) scans every minute, doctors can actually
watch as the iceball grows and can visualize when the tumor is
encased in ice. The researchers freeze the tumor for 15 minutes,
then let it thaw for 10 minutes and then re-freeze it, Dr. Sankar
said.
Follow-up studies with the MRI demonstrate that the area
of the tumor-which once was bright in the MRI scans-failed to
show any enhancement after the procedure, an indication that
the tissue had been killed, he said.
Contact Dr. Stuart Silverman sgsilverman@partners.org
12/03/2001; Doctor's Guide
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