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Stanford Researcher's Uncommon Approach To Common Cold Fights
Cancer
STANFORD, Calif. - Researchers at Stanford University Medical
Center have been spreading colds to cancer patients, all in the
hope of curing a deadly disease.
In the unusual technique, doctors
inject a modified cold virus into the liver as a way to kill
cancerous cells.
The major benefit of treatment with a modified cold virus is its
ability to target cancer while leaving normal cells unharmed.
"We want to kill the tumor but not at the expense of the patient,"
said Daniel Sze, MD, PhD, assistant professor of radiology at
Stanford.
Sze will present his findings April 8 at the Society
of Cardiovascular and Interventional Radiology annual scientific
meeting in Baltimore.
Thirty-five cancer patients received various doses of the live
virus, which was genetically weakened so that it was not as infectious
as a normal cold virus.
The patients suffered flu-like symptoms
for about a week - minor side-effects when compared to the nausea,
weakness and hair loss that results from chemotherapy. Of the
28 patients who received the highest virus dose, each was expected
to live only about six months but instead survived closer to
a year.
Many of their tumors also appeared to shrink and stopped
producing abnormal, tumor-associated proteins.
Sze said follow-up studies with more participants will provide
a better idea of exactly how effective the treatment may be.
"In this trial, we got a hint that it might actually benefit
people with cancer," he said, adding that in this phase I study,
the main concern was showing that the treatment is safe.
[04/11/2002; ScienceDaily]
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 British J Cancer, 2/05

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 Press Release, 3/14/05
Presented at 3rd Intl Meeting on
Replicating Oncolytic Virus Therapeutics

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 LINK to company making
'Coley Fluid'

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 LINK to article by Gar Hildebrand,
Gerson Research Organization

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 Cancer Letters, January 2008

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