Clin Analysis Thryoid Ca: Chernobyl-exposed Adults

A ñlinical analysis of thyroid cancer in adult patients exposed to ionising radiation due to the Chernobyl Nuclear Accident, Ukraine 1986.

M. Gorobeyko, S. Cherenko, O. Larin;

Ukrainian Research & Practical Centre of Endocrine Surgery, Kyiv, Ukraine

Abstract: Background: The world's worst nuclear disaster occurred at the Chernobyl in 1986.Thyroid cancer in children from Ukraine after 1986 has been recognised precisely as radio-induced disease,the question about development of thyroid cancer in adult patients still remains controversial.

The aim of the study is to compare the clinical and pathologic findings of surgical tumour pathology of thyroid in adults with or without history of irradiation due the Chernobyl disaster.

Methods: In the Centre of Endocrine Surgery,a total of 2363 adult patients who have been operated on their thyroid (benign and malignant tumours) with no evidence of radiation influence in their medical history (Group A).

311 patients were operated (born before 1969) with thyroid tumours and strict evidence of Chernobyl irradiation (Group B).

Patients of Group B represented three official categories of people affected by Chernobyl.Group:I-participants of the clean up operation (93 patients);II-people evacuated from the restricted area (82);III-inhabitants of polluted territories (136).

Results: Detailed information concerning this is to found in table.More distinct differences were observed in the 1st and 2nd subGroups of Group B patients.The most distinguished features were found in I category of B Group:T4-in47%,N1a-1b-in 62%,multifocality-in 41%.

Conclusion: We can speculate on the supposition that the stage of aggressiveness of thyroid cancer is dependant on the uptake of isotope of iodine during the first days of the catastrophe and during the work on Nuclear reactor.

Adults who are living in polluted by Ce-isotope lands do not have significant difference in the rate or aggressiveness of thyroid cancer with Group A.

The increasing rate of thyroid malignancy in those adults irradiated at Chernobyl demands the undertaking of the most radical mode of treatment in such patients.

Abstract No: 6103

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