Chemical Components & Their Effects: We know that Andrographis contains compounds that are analgesic (kills pain), antithrombotic (prevents blood clots), thrombolytic (breaks up blood clots), hypoglycemic (reduces blood sugar), and antipyretic (reduces fever). So, most of Andrographis' traditional uses have a scientific basis. Its most significant physiological effect is that of a "signal transducer," that is, it stops the unregulated cell growth caused by viruses (which may be why HIV sufferers are reported to show improvement with its regular use). Its most active component is andrographolide (see empirical formula at left), a colorless, bitter crystalline compound. Termed a "diterpene lactone" to describe its ringlike structure, this substance accumulates primarily in the brain, spleen, heart, and lungs. It is absorbed and excreted from the body quickly: 80% is removed within eight hours; 90%, within forty-eight hours. Effects on Cancer: Andrographis is a potent stimulator of immune response through two mechanisms: (1) antigen-specific response, that is, where antibodies are made to counteract an invading microorganism, and (2) nonspecific immune response, where the body's macrophage cells scavenge and destroy intruders. These mechanisms make Andrographis effective against a variety of infectious and cancer-causing agents. Source: Alpha Omega Labs www.altcancer.com Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.