"Body size and serum 25 hydroxy vitamin D response to oral supplements in healthy older adults," Blum M, Dallal GE, et al, (Address: Bess Dawson-Hughes, MD, Bone Metabolism Laboratory, Jean Mayer USDA, HNRC on Aging at Tufts University, 711 Washington Street, Boston, MA 02111, USA. E-mail: bess.dawson-hughes@tufts.edu ). Summary: In a study involving 257 healthy, ambulatory men and women aged 65 years or older, body size was found to be an important factor to consider when determining the amount of vitamin D needed to raise serum 25(OH)D levels to the desired level. Subjects were assigned to receive 700 IU/d (17.5 microg/d) vitamin D3 plus 500 mg/d (12.5 mmol/d) calcium, or a placebo, for a period of one year. After adjusting for various potentially confounding factors, change in 25(OH)D levels was found to be inversely associated with baseline body mass index (BMI). In addition, change in 25(OH)D level was inversely associated with other baseline anthropometric measurements as well. The authors conclude, "Our study implies that body size should be taken into account when estimating the amount of vitamin D intake needed to raise 25(OH)D to the desired level." Our source: www.VitaSearch.com J Am Coll Nutr, 2008; 27(2): 274-9. Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.