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ABSTRACT: Efficacy of Anastrozole in Male Breast Cancer
Metastatic breast carcinoma in men is usually responsive to
hormonal therapy. Most ablative and additive hormonal therapies
reported have had objective response rates in excess of 50%.
Anastrozole has excellent antitumor activity in postmenopausal
women, but no data exist on its efficacy in men. Medical records
for all men with a diagnosis of breast cancer who were treated at
M. D. Anderson from 1990 to 1999 were reviewed.
Five male patients
with metastatic breast cancer who were treated at M. D. Anderson
with anastrozole were identified. We now report on these five cases.
[06/06/2002; American Journal of Clinical Oncology]
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