Observation on the Treatment Effect of Agaricus Blazei Murrill to the Liver Function of Chronic Hepatitis Patients Originating from the mountain region of Piedade, Brazil, Agaricus blazei Murill has become quite popular there and in Asia as a panacea and also for its use in cancer. Interest was peaked when a much lower occurrence of adult diseases was found in this region. Research done in Japan in 1980's and 1990's appears to support these benefits. Studies demonstrate possible use in recovery from cancer as well as in prevention of the imbalance, while also shown promise for this mushroom's ability of lower blood glucose, serum cholesterol, and blood pressure, as well as that of strong immune enhancement. In Brazil, Agaricus is called "Cogmelo de Deus," Mushroom of God. A Chronic Hepatitis Patient in Japan who reported that after 3-month of treatment using Agaricus Blazei extract, the liver function was obviously improved, and there was a remarkable change in values including ALT, AST, bilirubin. It is obvious that Agaricus Blazei has a positive therapeutic effect. Agaricus Blazei influences all correlative perspectives of the liver function of chronic hepatitis, lowering GOT, GPT, and g-GTP. Serum connective cholic acid, serum ferritin, g-globulin, coagulation time after the treatment showed remarkable lowering. It is conceived that Agaricus Blazei has various therapeutic effects to hepatitis and presents a comprehensive control in the positive direction. The treatment was especially effective to 2 patients and effective to 8 patients of total 10 patients of experimental group, research conducted by K Kawagishi at the Anticancer Research in Japan. Through his experiment, it was found out that Agaricus Blazei Murrill extract is effective in promoting the recovery of hepatocytes of chronic hepatitis patients as well as in its immunological enhancement and anticancer activity. Agaricus contains the highest levels of Beta-1, 3-glucan of all known mushrooms, making it a very promising potential agent in cancer treatment activating macrophage, T-cell and NK-cell, increasing TNF-a production, inducing cancer cell apoptosis and cytotoxicity. It is rich in various polysaccharides and has shown to be highly supportive to the immune system, in both as immune enhancement and regulation. References: H. Kawagishi et al, Phytochemistry, 27(9):2777 (1988). H. Kawagishi et al, Carbohydrate Research, 186:267 (1989). T. Mizuno et al, Agric. Biol. Chem., 54(11):2889 (1990). T. Mizuno et al, Agric. Biol. Chem., 54(11):2897 (1990). H. Kawagishi et al, Carbohydrate Polymers, 12:393 (1990). K. Sugiyama et al, Nippon Eiyo Shokuryo Gakkaishi (Japanese), 45(3):265 (1992). H. Itoh et al, Japanese Journal of Pharmacology, Oct., 662 (1994). T. Mizuno, Food Reviews International, 11(1):167 (1995). H. Ito et al, Anticancer Research, Jan. - Feb., 17(1A):277 (1997). Y. Fujimiya et al, cancer Immunol Immunother, 46:147 (1998). Info sent by www.agaricus.net Food Chem Toxicol, 6/04 Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.