Margaret E. Wright, Susan T. Mayne and Michael CR Alavanja Yale University School of Medicine, Department of Epidemiology and Public Health, Division of Cancer Epidemiology and Genetics, NCI Effects of fruit and vegetable consumption on the association between residential radon exposure and lung cancer risk were examined using data from a population-based case-control study of lung cancer in Missouri women, most of whom were current or former smokers. Data were available for 356 newly diagnosed lung cancer cases and 470 controls frequency matched to cases based on age. A modified food-frequency questionnaire was used to obtain information about usual diet 2-3 years prior to interview. 20-year-time-weighted-average residential radon concentrations were assessed with CR-39 alpha-particle detectors (surface monitors), which appear to capture cumulative radon exposure more accurately than standard indoor radon detectors. Women exposed to high radon levels (>median vs. In stratified analyses, low consumption of several plant food groupings exacerbated the risk of lung cancer associated with high residential radon exposure. For example, the odds ratio for high vs. low radon exposure was 1.66 (95% CI: 1.11-2.49) in women with low total vegetable/fruit juice consumption, and 1.15 (95%CI 0.75-1.78) in women with high total vegetable/fruit/juice consumption. Joint effects of radon exposure with consumption of individual plant food groupings were not, however, statistically significant with multiplicative interaction models. These results suggest that nonsmoking and smoking women exposed to high levels of residential radon may have an even higher risk of lung cancer if they consume inadequate amounts of fruits and vegetables. Remember we are NOT Doctors and have NO medical training. This site is like an Encylopedia - there are many pages, many links on many topics. Support our work with any size DONATION - see left side of any page - for how to donate. You can help raise awareness of CAM.